Ifu ya L-Tyrosine
l-tyrosine
Intangiriro ngufi
Tyrosine (mu magambo ahinnye nka Tyr cyangwa Y) cyangwa 4-hydroxyphenylalanine ni imwe muri aside amine 22 zikoreshwa n'uturemangingo mu gukora poroteyine. Ishobora gukoreshwa mu gukora poroteyine mu turemangingo, hamwe na codons UAC na UAU. Ni aside amine idakenewe irimo amatsinda y'uruhande rw'inyuma kandi ishobora gukorwa n'umubiri w'umuntu. Ijambo 'tyrosine' rikomoka ku ijambo ry'Ikigiriki tyros, risobanura foromaje. Mu ntangiriro z'ikinyejana cya 19, yavumbuwe bwa mbere n'umuhanga mu bya shimi w'Umudage Eustus von Libich muri foromaje ya casein, kandi iyo ikoreshejwe nk'itsinda ry'uruhande, yitwa tyrosine.
imikorere
Uretse kuba aside amine ya poroteyine, tyrosine igira uruhare runini mu kohereza ibimenyetso muri poroteyine binyuze mu matsinda y’imikorere ya phenolic. Akazi kayo ni nk'agakoresho k’amatsinda ya fosifate yoherezwa na poroteyine kinase (ibyo bita tyrosine kinase receptors), mu gihe fosifate y’amatsinda ya hydroxyl ihindura imikorere ya poroteyine igamije.
Tyrosine kandi igira uruhare runini muri fotositemu, ikora nk'umutanga wa electron mu kugabanya uburyo chlorophyll ya oxidized ikorwa muri chloroplasts (Photosystem II), gukuraho protonation y'amatsinda ya phenolic OH, ndetse no kugabanukaho amatsinda ane y'ingenzi ya manganese muri Photosystem II.
Inkomoko y'imirire
Tyrosine ishobora gukorwa muri phenylalanine mu mubiri kandi iboneka mu biribwa byinshi birimo poroteyine nyinshi nka inkoko, itunguru, amafi, amata, yawurute, foromaje, foromaje, ubunyobwa, amande, imbuto z'ibihaza, sesame, soya, ibishyimbo bya lima, avoka n'imineke.
L-tyrosine ni aside amine itari ngombwa kandi ni kimwe mu bintu by'ingenzi mu nzira ya methionine metabolism. Iboneka cyane mu binyabuzima kandi igira uruhare runini mu mikorere myinshi ya biyoloji.
L-tyrosine ni igice cya poroteyine kandi igira uruhare mu ikorwa rya poroteyine. Ni kandi igikoresho cy’ibanze cy’ibintu bitandukanye bikora ku buzima, harimo na neurotransmitters za catecholamine nka dopamine, norepinephrine, na adrenaline, ndetse n’imisemburo ya tiroyide na melanin.
Byongeye kandi, L-tyrosine inagira uruhare mu gukora molekile z'ingenzi za biyoloji binyuze mu ruhererekane rwa enzymes mu mubiri, nka tyrosine kinase na tyrosine hydroxylase, zigira uruhare mu nzira z'itumanaho rya kinase no mu kugenzura imikorere y'umubiri.
Kurya L-tyrosine bishobora kuboneka binyuze mu mirire, hamwe n'ibiribwa byinshi birimo imbuto, imbuto, inyama, amafi, n'ibikomoka ku mata. Byongeye kandi, L-tyrosine ishobora kandi guhindurwa ikava mu yindi aside amine, phenylalanine, binyuze mu nzira yo gukora tyrosine mu mubiri.
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